Self-complementary AAV2.5-BMP2-coated Femoral Allografts Mediated Superior Bone Healing Versus Live Autografts in Mice With Equivalent Biomechanics to Unfractured Femur

Structural allografts used for critical bone defects have limited osteogenic properties for biointegration. Although ex vivo tissue-engineered constructs expressing bone morphogenetic protein-2 (BMP2) have demonstrated efficacy in critical defect models, similar success has not been achieved with of...

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Bibliografiske detaljer
Main Authors: Yazici, Cemal, Takahata, Masahiko, Reynolds, David G, Xie, Chao, Samulski, R Jude, Samulski, Jade, Beecham, E Jeffrey, Gertzman, Arthur A, Spilker, Mark, Zhang, Xinping, O'Keefe, Regis J, Awad, Hani A, Schwarz, Edward M
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2011
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3149158/
https://ncbi.nlm.nih.gov/pubmed/21206485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2010.294
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