Correct Interpretation of Comprehensive Phosphorylation Dynamics Requires Normalization by Protein Expression Changes

The interpretation of quantitative phosphoproteomics studies is complicated because each differential phosphorylation event integrates both changes in protein expression and phosphorylation. Here we investigated this phenomenon by performing parallel comparisons of protein expression and phosphoryla...

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Detaylı Bibliyografya
Asıl Yazarlar: Wu, Ronghu, Dephoure, Noah, Haas, Wilhelm, Huttlin, Edward L., Zhai, Bo, Sowa, Mathew E., Gygi, Steven P.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The American Society for Biochemistry and Molecular Biology 2011
Konular:
Technological Innovation and Resources
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3149096/
https://ncbi.nlm.nih.gov/pubmed/21551504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M111.009654
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