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Correct Interpretation of Comprehensive Phosphorylation Dynamics Requires Normalization by Protein Expression Changes

The interpretation of quantitative phosphoproteomics studies is complicated because each differential phosphorylation event integrates both changes in protein expression and phosphorylation. Here we investigated this phenomenon by performing parallel comparisons of protein expression and phosphoryla...

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Detalhes bibliográficos
Main Authors: Wu, Ronghu, Dephoure, Noah, Haas, Wilhelm, Huttlin, Edward L., Zhai, Bo, Sowa, Mathew E., Gygi, Steven P.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3149096/
https://ncbi.nlm.nih.gov/pubmed/21551504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M111.009654
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