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Evaluation of HCD- and CID-type Fragmentation Within Their Respective Detection Platforms For Murine Phosphoproteomics

Protein phosphorylation modulates a myriad of biological functions, and its regulation is vital for proper cellular activity. Mass spectrometry is the enabling tool for phosphopeptide analysis, where recent instrumentation advances in both speed and sensitivity in linear ion trap and orbitrap techno...

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Detalhes bibliográficos
Main Authors: Jedrychowski, Mark P., Huttlin, Edward L., Haas, Wilhelm, Sowa, Mathew E., Rad, Ramin, Gygi, Steven P.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3237076/
https://ncbi.nlm.nih.gov/pubmed/21917720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M111.009910
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