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Deep and Highly Sensitive Proteome Coverage by LC-MS/MS Without Prefractionation
In-depth MS-based proteomics has necessitated fractionation of either proteins or peptides or both, often requiring considerable analysis time. Here we employ long liquid chromatography runs with high resolution coupled to an instrument with fast sequencing speed to investigate how much of the prote...
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| Główni autorzy: | , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
The American Society for Biochemistry and Molecular Biology
2011
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3149084/ https://ncbi.nlm.nih.gov/pubmed/21586754 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M110.003699 |
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