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Deep and Highly Sensitive Proteome Coverage by LC-MS/MS Without Prefractionation
In-depth MS-based proteomics has necessitated fractionation of either proteins or peptides or both, often requiring considerable analysis time. Here we employ long liquid chromatography runs with high resolution coupled to an instrument with fast sequencing speed to investigate how much of the prote...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Biochemistry and Molecular Biology
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3149084/ https://ncbi.nlm.nih.gov/pubmed/21586754 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M110.003699 |
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