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Proteomic Changes Resulting from Gene Copy Number Variations in Cancer Cells

Along the transformation process, cells accumulate DNA aberrations, including mutations, translocations, amplifications, and deletions. Despite numerous studies, the overall effects of amplifications and deletions on the end point of gene expression—the level of proteins—is generally unknown. Here w...

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Detalhes bibliográficos
Main Authors: Geiger, Tamar, Cox, Juergen, Mann, Matthias
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2932691/
https://ncbi.nlm.nih.gov/pubmed/20824076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1001090
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