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Proteomic Changes Resulting from Gene Copy Number Variations in Cancer Cells

Along the transformation process, cells accumulate DNA aberrations, including mutations, translocations, amplifications, and deletions. Despite numerous studies, the overall effects of amplifications and deletions on the end point of gene expression—the level of proteins—is generally unknown. Here w...

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Bibliografische gegevens
Hoofdauteurs: Geiger, Tamar, Cox, Juergen, Mann, Matthias
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2010
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2932691/
https://ncbi.nlm.nih.gov/pubmed/20824076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1001090
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