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Proteomic Changes Resulting from Gene Copy Number Variations in Cancer Cells

Along the transformation process, cells accumulate DNA aberrations, including mutations, translocations, amplifications, and deletions. Despite numerous studies, the overall effects of amplifications and deletions on the end point of gene expression—the level of proteins—is generally unknown. Here w...

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Библиографические подробности
Главные авторы: Geiger, Tamar, Cox, Juergen, Mann, Matthias
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2010
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2932691/
https://ncbi.nlm.nih.gov/pubmed/20824076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1001090
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