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Proteomic Changes Resulting from Gene Copy Number Variations in Cancer Cells

Along the transformation process, cells accumulate DNA aberrations, including mutations, translocations, amplifications, and deletions. Despite numerous studies, the overall effects of amplifications and deletions on the end point of gene expression—the level of proteins—is generally unknown. Here w...

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Hlavní autoři: Geiger, Tamar, Cox, Juergen, Mann, Matthias
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2932691/
https://ncbi.nlm.nih.gov/pubmed/20824076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1001090
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