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Proteomic Changes Resulting from Gene Copy Number Variations in Cancer Cells

Along the transformation process, cells accumulate DNA aberrations, including mutations, translocations, amplifications, and deletions. Despite numerous studies, the overall effects of amplifications and deletions on the end point of gene expression—the level of proteins—is generally unknown. Here w...

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Autors principals: Geiger, Tamar, Cox, Juergen, Mann, Matthias
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2932691/
https://ncbi.nlm.nih.gov/pubmed/20824076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1001090
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