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Sox9-Haploinsufficiency Causes Glucose Intolerance in Mice

The HMG box transcription factor Sox9 plays a critical role in progenitor cell expansion during pancreas organogenesis and is required for proper endocrine cell development in the embryo. Based on in vitro studies it has been suggested that Sox9 controls expression of a network of important developm...

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Autors principals: Dubois, Claire L., Shih, Hung Ping, Seymour, Philip A., Patel, Nisha A., Behrmann, James M., Ngo, Victoria, Sander, Maike
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3149078/
https://ncbi.nlm.nih.gov/pubmed/21829703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0023131
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