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Differential effect of CLK SR Kinases on HIV-1 gene expression: potential novel targets for therapy

BACKGROUND: RNA processing plays a critical role in the replication of HIV-1, regulated in part through the action of host SR proteins. To explore the impact of modulating SR protein activity on virus replication, the effect of increasing or inhibiting the activity of the Cdc2-like kinase (CLK) fami...

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Autors principals: Wong, Raymond, Balachandran, Ahalya, Mao, Annie YQ, Dobson, Wendy, Gray-Owen, Scott, Cochrane, Alan
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3148977/
https://ncbi.nlm.nih.gov/pubmed/21682887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-8-47
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