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Differential Response of Primary and Immortalized CD4(+) T Cells to Neisseria gonorrhoeae-Induced Cytokines Determines the Effect on HIV-1 Replication

To compare the effect of gonococcal co-infection on immortalized versus primary CD4(+) T cells the Jurkat cell line or freshly isolated human CD4(+) T cells were infected with the HIV-1 X4 strain NL4-3. These cells were exposed to whole gonococci, supernatants from gonococcal-infected PBMCs, or N. g...

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Detalhes bibliográficos
Main Authors: Dobson-Belaire, Wendy N., Cochrane, Alan, Ostrowski, Mario A., Gray-Owen, Scott D.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3081295/
https://ncbi.nlm.nih.gov/pubmed/21526113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0018133
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