Anti-tumor activity and signaling events triggered by the isothiocyanates, sulforaphane and phenethyl isothiocyanate, in multiple myeloma

BACKGROUND: Isothiocyanates, a family of phytochemicals found in cruciferous vegetables, have cytotoxic effects against several types of tumor cells. Multiple myeloma is a fatal disease characterized by clonal proliferation of plasma cells in the bone marrow. The growing body of preclinical informat...

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Main Authors: Jakubikova, Jana, Cervi, David, Ooi, Melissa, Kim, Kihyun, Nahar, Sabikun, Klippel, Steffen, Cholujova, Dana, Leiba, Merav, Daley, John F., Delmore, Jake, Negri, Joseph, Blotta, Simona, McMillin, Douglas W., Hideshima, Teru, Richardson, Paul G., Sedlak, Jan, Anderson, Kenneth C., Mitsiades, Constantine S.
Formato: Artigo
Idioma:Inglês
Publicado: Ferrata Storti Foundation 2011
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Original Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3148911/
https://ncbi.nlm.nih.gov/pubmed/21712538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2010.029363
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