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Notch signaling prevents mucous metaplasia in mouse conducting airways during postnatal development
Goblet cell metaplasia and mucus overproduction contribute to the pathogenesis of chronic lung diseases, including asthma and chronic obstructive pulmonary disease (COPD). Notch signaling regulates cell fate decisions and is crucial in controlling goblet cell differentiation in the gut epithelium. L...
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| Main Authors: | , , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Company of Biologists
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3148592/ https://ncbi.nlm.nih.gov/pubmed/21791528 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.063727 |
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