Notch signaling prevents mucous metaplasia in mouse conducting airways during postnatal development

Goblet cell metaplasia and mucus overproduction contribute to the pathogenesis of chronic lung diseases, including asthma and chronic obstructive pulmonary disease (COPD). Notch signaling regulates cell fate decisions and is crucial in controlling goblet cell differentiation in the gut epithelium. L...

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Hlavní autoři: Tsao, Po-Nien, Wei, Shu-Chen, Wu, Ming-Fang, Huang, Miao-Tzu, Lin, Hsien-Yi, Lee, Ming-Cheng, Lin, Kurt Ming-Chao, Wang, I-Jong, Kaartinen, Vesa, Yang, Liang-Tung, Cardoso, Wellington V.
Médium: Artigo
Jazyk:Inglês
Vydáno: Company of Biologists 2011
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3148592/
https://ncbi.nlm.nih.gov/pubmed/21791528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.063727
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