Notch signaling prevents mucous metaplasia in mouse conducting airways during postnatal development

Goblet cell metaplasia and mucus overproduction contribute to the pathogenesis of chronic lung diseases, including asthma and chronic obstructive pulmonary disease (COPD). Notch signaling regulates cell fate decisions and is crucial in controlling goblet cell differentiation in the gut epithelium. L...

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Detaylı Bibliyografya
Asıl Yazarlar: Tsao, Po-Nien, Wei, Shu-Chen, Wu, Ming-Fang, Huang, Miao-Tzu, Lin, Hsien-Yi, Lee, Ming-Cheng, Lin, Kurt Ming-Chao, Wang, I-Jong, Kaartinen, Vesa, Yang, Liang-Tung, Cardoso, Wellington V.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Company of Biologists 2011
Konular:
Research Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3148592/
https://ncbi.nlm.nih.gov/pubmed/21791528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.063727
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