Notch signaling prevents mucous metaplasia in mouse conducting airways during postnatal development

Goblet cell metaplasia and mucus overproduction contribute to the pathogenesis of chronic lung diseases, including asthma and chronic obstructive pulmonary disease (COPD). Notch signaling regulates cell fate decisions and is crucial in controlling goblet cell differentiation in the gut epithelium. L...

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Bibliographische Detailangaben
Hauptverfasser: Tsao, Po-Nien, Wei, Shu-Chen, Wu, Ming-Fang, Huang, Miao-Tzu, Lin, Hsien-Yi, Lee, Ming-Cheng, Lin, Kurt Ming-Chao, Wang, I-Jong, Kaartinen, Vesa, Yang, Liang-Tung, Cardoso, Wellington V.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Company of Biologists 2011
Schlagworte:
Research Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3148592/
https://ncbi.nlm.nih.gov/pubmed/21791528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.063727
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