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Overexpression of MMP-9 and HIF-1α in Breast Cancer Cells under Hypoxic Conditions
PURPOSE: Hypoxia, which is a loss of oxygen in tissues, is a common condition in solid tumors due to the tumor outgrowing existing vasculature. Under hypoxic conditions, hypoxia-inducible factor (HIF)-1α rapidly accumulates and transactivates hundreds of genes, such as matrix metalloproteinases (MMP...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Korean Breast Cancer Society
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3148536/ https://ncbi.nlm.nih.gov/pubmed/21847402 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4048/jbc.2011.14.2.88 |
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