Overexpression of MMP-9 and HIF-1α in Breast Cancer Cells under Hypoxic Conditions

PURPOSE: Hypoxia, which is a loss of oxygen in tissues, is a common condition in solid tumors due to the tumor outgrowing existing vasculature. Under hypoxic conditions, hypoxia-inducible factor (HIF)-1α rapidly accumulates and transactivates hundreds of genes, such as matrix metalloproteinases (MMP...

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Detalhes bibliográficos
Main Authors: Choi, Jae Young, Jang, Yeon Soo, Min, Sun Young, Song, Jeong Yoon
Formato: Artigo
Idioma:Inglês
Publicado em: Korean Breast Cancer Society 2011
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3148536/
https://ncbi.nlm.nih.gov/pubmed/21847402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4048/jbc.2011.14.2.88
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