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Endothelial cell-specific aryl hydrocarbon receptor knockout mice exhibit hypotension mediated, in part, by an attenuated angiotensin II responsiveness

Hypotension in aryl hydrocarbon receptor knockout mice (ahr(−/−)) is mediated, in part, by a reduced contribution of angiotensin (Ang) II to basal blood pressure (BP). Since AHR is highly expressed in endothelial cells (EC), we hypothesized that EC-specific ahr(−/−) (ECahr(−/−)) mice would exhibit a...

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Detalhes bibliográficos
Main Authors: Agbor, Larry N., Elased, Khalid M., Walker, Mary K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3148414/
https://ncbi.nlm.nih.gov/pubmed/21684261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2011.06.011
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