An activated renin-angiotensin system maintains normal blood pressure in aryl hydrocarbon receptor heterozygous mice but not in null mice

It has been postulated that fetal vascular abnormalities in aryl hydrocarbon receptor null (ahr(−/−)) mice may alter cardiovascular homeostasis in adulthood. We tested the hypothesis that blood pressure regulation in adult heterozygous mice (ahr(+/−)) would be normal, compared to ahr(−/−) mice, sinc...

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Autors principals: Zhang, Nan, Agbor, Larry N., Scott, Jason A., Zalobowski, Tyler, Elased, Khalid M., Trujillo, Alicia, Duke, Melissa Skelton, Wolf, Valerie, Walsh, Mary T., Born, Jerry L., Felton, Linda A., Wang, J, Wang, Wei, Kanagy, Nancy L., Walker, Mary K.
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2867364/
https://ncbi.nlm.nih.gov/pubmed/20359465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2010.03.023
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