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PTEN positively regulates UVB-induced DNA damage repair

Non-melanoma skin cancer is the most common cancer in the U.S., where DNA-damaging UVB radiation from the sun remains the major environmental risk factor. However, the critical genetic targets of UVB radiation are undefined. Here we show that attenuating PTEN in epidermal keratinocytes is a predispo...

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Autors principals: Ming, Mei, Feng, Li, Shea, Christopher R., Soltani, Keyoumars, Zhao, Baozhong, Han, Weinong, Smart, Robert C., Trempus, Carol S., He, Yu-Ying
Format: Artigo
Idioma:Inglês
Publicat: 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3148338/
https://ncbi.nlm.nih.gov/pubmed/21771908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-10-4614
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