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PTEN positively regulates UVB-induced DNA damage repair

Non-melanoma skin cancer is the most common cancer in the U.S., where DNA-damaging UVB radiation from the sun remains the major environmental risk factor. However, the critical genetic targets of UVB radiation are undefined. Here we show that attenuating PTEN in epidermal keratinocytes is a predispo...

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Detalhes bibliográficos
Main Authors: Ming, Mei, Feng, Li, Shea, Christopher R., Soltani, Keyoumars, Zhao, Baozhong, Han, Weinong, Smart, Robert C., Trempus, Carol S., He, Yu-Ying
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3148338/
https://ncbi.nlm.nih.gov/pubmed/21771908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-10-4614
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