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Regulation of global genome nucleotide excision repair by SIRT1 through xeroderma pigmentosum C
Disruption of the nucleotide excision repair (NER) pathway by mutations can cause xeroderma pigmentosum, a syndrome predisposing affected individuals to development of skin cancer. The xeroderma pigmentosum C (XPC) protein is essential for initiating global genome NER by recognizing the DNA lesion a...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3012476/ https://ncbi.nlm.nih.gov/pubmed/21149730 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1010377108 |
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