Nucleotide Excision Repair by Mutant Xeroderma Pigmentosum Group A (XPA) Proteins with Deficiency in Interaction with RPA

The xeroderma pigmentosum group A protein (XPA) is a core component of nucleotide excision repair (NER). To coordinate early stage NER, XPA interacts with various proteins, including replication protein A (RPA), ERCC1, DDB2, and TFIIH, in addition to UV-damaged or chemical carcinogen-damaged DNA. In...

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Bibliographic Details
Main Authors: Saijo, Masafumi, Takedachi, Arato, Tanaka, Kiyoji
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2011
Subjects:
DNA and Chromosomes
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3037661/
https://ncbi.nlm.nih.gov/pubmed/21148310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.172916
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