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DDB2 Complex-Mediated Ubiquitylation around DNA Damage Is Oppositely Regulated by XPC and Ku and Contributes to the Recruitment of XPA

UV-damaged-DNA-binding protein (UV-DDB) is a heterodimer comprised of DDB1 and DDB2 and integrated in a complex that includes a ubiquitin ligase component, cullin 4A, and Roc1. Here we show that the ubiquitin ligase activity of the DDB2 complex is required for efficient global genome nucleotide exci...

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Hlavní autoři: Takedachi, Arato, Saijo, Masafumi, Tanaka, Kiyoji
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2876528/
https://ncbi.nlm.nih.gov/pubmed/20368362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01460-09
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