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Herpes Simplex Virus Immediate-Early Protein ICP0 Is Targeted by SIAH-1 for Proteasomal Degradation

Herpes simplex virus (HSV) immediate-early protein ICP0 is a transcriptional activator with E3 ubiquitin ligase activity that induces the degradation of ND10 proteins, including the promyelocytic leukemia protein (PML) and Sp100. Moreover, ICP0 has a role in the derepression of viral genomes and in...

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Detalhes bibliográficos
Main Authors: Nagel, Claus-Henning, Albrecht, Nina, Milovic-Holm, Kristijana, Mariyanna, Lakshmikanth, Keyser, Britta, Abel, Bettina, Weseloh, Britta, Hofmann, Thomas G., Eibl, Martha M., Hauber, Joachim
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3147933/
https://ncbi.nlm.nih.gov/pubmed/21632771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02207-10
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