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Herpes Simplex Virus Type 1 Immediate-Early Protein ICP27 Is Required for Efficient Incorporation of ICP0 and ICP4 into Virions

Early in infection, herpes simplex virus type 1 (HSV-1) immediate-early (IE) proteins ICP0 and ICP4 localize to the nucleus, where they stimulate viral transcription. Later in infection, ICP0 and to a lesser extent ICP4 accumulate in the cytoplasm, but their biological role there is unknown. Previou...

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Detalhes bibliográficos
Main Authors: Sedlackova, Lenka, Rice, Stephen A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2224399/
https://ncbi.nlm.nih.gov/pubmed/17959681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01588-07
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