ICP22 Is Required for Wild-Type Composition and Infectivity of Herpes Simplex Virus Type 1 Virions

The immediate-early regulatory protein ICP22 is required for efficient replication of herpes simplex virus type 1 in some cell types (permissive) but not in others (restrictive). In mice infected via the ocular route, the pathogenesis of an ICP22(−) virus, 22/n199, was altered relative to that of wi...

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Hlavní autoři: Orlando, Joseph S., Balliet, John W., Kushnir, Anna S., Astor, Todd L., Kosz-Vnenchak, Magdalena, Rice, Stephen A., Knipe, David M., Schaffer, Priscilla A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2006
Témata:
Genome Replication and Regulation of Viral Gene Expression
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1617265/
https://ncbi.nlm.nih.gov/pubmed/16973544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01061-06
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