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Herpes Simplex Virus Type 1 ICP0 Phosphorylation Mutants Impair the E3 Ubiquitin Ligase Activity of ICP0 in a Cell Type-Dependent Manner

Herpes simplex virus type 1 (HSV-1) infected cell protein 0 (ICP0) is a 110-kDa nuclear phosphoprotein that is required for both the efficient initiation of lytic infection and the reactivation of quiescent viral genomes from latency. The ability of ICP0 to act as a potent viral transactivator is me...

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Bibliografski detalji
Glavni autori: Boutell, Chris, Everett, Roger, Hilliard, Joshua, Schaffer, Priscilla, Orr, Anne, Davido, David
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 2008
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2573210/
https://ncbi.nlm.nih.gov/pubmed/18715910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01063-08
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