Herpes Simplex Virus Type 1 Immediate-Early Protein ICP0 and Its Isolated RING Finger Domain Act as Ubiquitin E3 Ligases In Vitro

Proteasome-dependent degradation of ubiquitinated proteins plays a key role in many important cellular processes. Ubiquitination requires the E1 ubiquitin activating enzyme, an E2 ubiquitin conjugating enzyme, and frequently a substrate-specific ubiquitin protein ligase (E3). One class of E3 ubiquit...

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Bibliographic Details
Main Authors: Boutell, Chris, Sadis, Seth, Everett, Roger D.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2002
Subjects:
Virus-Cell Interactions
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC136846/
https://ncbi.nlm.nih.gov/pubmed/11752173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.2.841-850.2002
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