Interaction between the cellular E3 ubiquitin ligase SIAH-1 and the viral immediate-early protein ICP0 enables efficient replication of Herpes Simplex Virus type 2 in vivo

Herpes Simplex Virus type 2 (HSV-2) is a neurotropic human pathogen. Upon de novo infection, the viral infected cell protein 0 (ICP0) is immediately expressed and interacts with various cellular components during the viral replication cycle. ICP0 is a multifunctional regulatory protein that has been...

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Vydáno v:PLoS One
Hlavní autoři: Czechowicz, Julia S., Nagel, Claus-Henning, Voges, Maike, Spohn, Michael, Eibl, Martha M., Hauber, Joachim
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2018
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6078308/
https://ncbi.nlm.nih.gov/pubmed/30080903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0201880
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