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FLASH links the CD95 signaling pathway to the cell nucleus and nuclear bodies

Caspase-8-binding protein FLICE-associated huge protein (FLASH) has been proposed to regulate death receptor CD95-induced apoptosis through facilitating caspase-8 activation at the death-inducing signaling complex. Here, we found that FLASH interacts with the PML nuclear body component Sp100 and pre...

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Detalhes bibliográficos
Main Authors: Milovic-Holm, Kristijana, Krieghoff, Eva, Jensen, Kirsten, Will, Hans, Hofmann, Thomas G
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1783462/
https://ncbi.nlm.nih.gov/pubmed/17245429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601504
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