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FLASH links the CD95 signaling pathway to the cell nucleus and nuclear bodies

Caspase-8-binding protein FLICE-associated huge protein (FLASH) has been proposed to regulate death receptor CD95-induced apoptosis through facilitating caspase-8 activation at the death-inducing signaling complex. Here, we found that FLASH interacts with the PML nuclear body component Sp100 and pre...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Milovic-Holm, Kristijana, Krieghoff, Eva, Jensen, Kirsten, Will, Hans, Hofmann, Thomas G
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2007
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1783462/
https://ncbi.nlm.nih.gov/pubmed/17245429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601504
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