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The RPB2 Flap Loop of Human RNA Polymerase II Is Dispensable for Transcription Initiation and Elongation

The flap domain of multisubunit RNA polymerases (RNAPs), also called the wall, forms one side of the RNA exit channel. In bacterial RNAP, the mobile part of the flap is called the flap tip and makes essential contacts with initiation and elongation factors. Cocrystal structures suggest that the orth...

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Main Authors: Palangat, Murali, Grass, Jeffrey A., Langelier, Marie-France, Coulombe, Benoit, Landick, Robert
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Microbiology 2011
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3147802/
https://ncbi.nlm.nih.gov/pubmed/21670157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.05318-11
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