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A negative elongation factor for human RNA polymerase II inhibits the anti-arrest transcript-cleavage factor TFIIS

Formation of productive transcription complexes after promoter escape by RNA polymerase II is a major event in eukaryotic gene regulation. Both negative and positive factors control this step. The principal negative elongation factor (NELF) contains four polypeptides and requires for activity the tw...

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Autors principals: Palangat, Murali, Renner, Dan B., Price, David H., Landick, Robert
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2005
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1257689/
https://ncbi.nlm.nih.gov/pubmed/16214896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0409405102
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