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Talin1 Regulates Integrin Turnover To Promote Embryonic Epithelial Morphogenesis
Talin is a cytoskeletal protein that binds to integrin β cytoplasmic tails and regulates integrin activation. Talin1 ablation in mice disrupts gastrulation and causes embryonic lethality. However, the role of talin in mammalian epithelial morphogenesis is poorly understood. Here we demonstrate that...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3147785/ https://ncbi.nlm.nih.gov/pubmed/21670148 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01403-10 |
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