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Bnip3 and AIF cooperate to induce apoptosis and cavitation during epithelial morphogenesis
Apoptosis is an essential step in cavitation during embryonic epithelial morphogenesis, but its mechanisms are largely unknown. In this paper, we used embryonic stem cell–differentiated embryoid bodies (EBs) as a model and found that Bnip3 (Bcl-2/adenovirus E1B 19-kD interacting protein), a BH3-only...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3392936/ https://ncbi.nlm.nih.gov/pubmed/22753893 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201111063 |
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