Novel Method for Simultaneous Quantification of Phenotypic Resistance to Maturation, Protease, Reverse Transcriptase, and Integrase HIV Inhibitors Based on 3′Gag(p2/p7/p1/p6)/PR/RT/INT-Recombinant Viruses: a Useful Tool in the Multitarget Era of Antiretroviral Therapy

Twenty-six antiretroviral drugs (ARVs), targeting five different steps in the life cycle of the human immunodeficiency virus type 1 (HIV-1), have been approved for the treatment of HIV-1 infection. Accordingly, HIV-1 phenotypic assays based on common cloning technology currently employ three, or pos...

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Detalhes bibliográficos
Main Authors: Weber, Jan, Vazquez, Ana C., Winner, Dane, Rose, Justine D., Wylie, Doug, Rhea, Ariel M., Henry, Kenneth, Pappas, Jennifer, Wright, Alison, Mohamed, Nizar, Gibson, Richard, Rodriguez, Benigno, Soriano, Vicente, King, Kevin, Arts, Eric J., Olivo, Paul D., Quiñones-Mateu, Miguel E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3147656/
https://ncbi.nlm.nih.gov/pubmed/21628544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00396-11
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