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Foamy Virus Gag p71-p68 Cleavage Is Required for Template Switch of the Reverse Transcriptase

In contrast to orthoretroviruses, processing of foamy viral p71 Gag is limited to a single cleavage site. Nevertheless, Gag maturation is essential for infectivity, but deletion of p3 results in a modest drop in infectivity. Here, we show that Gag processing of p71 to p68 and p3 is essential for ful...

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Detalhes bibliográficos
Main Authors: Spannaus, Ralf, Schneider, Anna, Hartl, Maximilian J., Wöhrl, Birgitta M., Bodem, Jochen
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3700290/
https://ncbi.nlm.nih.gov/pubmed/23616664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00833-13
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