Regulation of Foamy Virus Protease Activity by Viral RNA: a Novel and Unique Mechanism among Retroviruses

Foamy viruses (FVs) synthesize the Pol precursor protein from a specific transcript. Thus, in contrast to what was found for orthoretroviruses, e.g., human immunodeficiency virus, no Gag-Pol precursor protein is synthesized. Foamy viral Pol consists of a protease (PR) domain, a reverse transcriptase...

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Bibliografske podrobnosti
Main Authors: Hartl, Maximilian J., Bodem, Jochen, Jochheim, Fabian, Rethwilm, Axel, Rösch, Paul, Wöhrl, Birgitta M.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2011
Teme:
Structure and Assembly
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3126251/
https://ncbi.nlm.nih.gov/pubmed/21325405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02211-10
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