Novel Inhibitors of InhA Efficiently Kill Mycobacterium tuberculosis under Aerobic and Anaerobic Conditions

Drug resistance in Mycobacterium tuberculosis has become a serious global health threat, which is now complicated by the emergence of extensively drug-resistant strains. New drugs that are active against drug-resistant tuberculosis (TB) are needed. We chose to search for new inhibitors of the enoyl-...

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Autors principals: Vilchèze, Catherine, Baughn, Anthony D., Tufariello, JoAnn, Leung, Lawrence W., Kuo, Mack, Basler, Christopher F., Alland, David, Sacchettini, James C., Freundlich, Joel S., Jacobs, William R.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2011
Matèries:
Susceptibility
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3147652/
https://ncbi.nlm.nih.gov/pubmed/21628538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00266-11
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