Distinctive Immunomodulatory and Inflammatory Properties of the Escherichia coli Type II Heat-Labile Enterotoxin LT-IIa and Its B Pentamer following Intradermal Administration

The type I and type II heat-labile enterotoxins (LT-I and LT-II) are strong mucosal adjuvants when they are coadministered with soluble antigens. Nonetheless, data on the parenteral adjuvant activities of LT-II are still limited. Particularly, no previous study has evaluated the adjuvant effects and...

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Hauptverfasser: Mathias-Santos, Camila, Rodrigues, Juliana F., Sbrogio-Almeida, Maria Elisabete, Connell, Terry D., Ferreira, Luís C. S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2011
Schlagworte:
Vaccine Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3147343/
https://ncbi.nlm.nih.gov/pubmed/21677110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00012-11
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