The Type II Heat-Labile Enterotoxins LT-IIa and LT-IIb and Their Respective B Pentamers Differentially Induce and Regulate Cytokine Production in Human Monocytic Cells

The type II heat-labile enterotoxins, LT-IIa and LT-IIb, exhibit potent adjuvant properties. However, little is known about their immunomodulatory activities upon interaction with innate immune cells, unlike the widely studied type I enterotoxins that include cholera toxin (CT). We therefore investi...

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Detalhes bibliográficos
Main Authors: Hajishengallis, George, Nawar, Hesham, Tapping, Richard I., Russell, Michael W., Connell, Terry D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC523043/
https://ncbi.nlm.nih.gov/pubmed/15501764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.72.11.6351-6358.2004
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