Enhanced antigen uptake by dendritic cells induced by the B pentamer of the type II heat-labile enterotoxin LT-IIa requires engagement of TLR2

The potent mucosal adjuvant properties of the type II heat-labile enterotoxin LT-IIa of Escherichia coli are dependent upon binding of the B pentamer of the enterotoxin (LT-IIa-B(5)) to ganglioside receptors on immunocompetent cells. To evaluate the immunomodulatory activities of LT-IIa-B(5), in vit...

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Main Authors: Lee, Chang Hoon, Nawar, Hesham F., Mandell, Lorrie, Liang, Shuang, Hajishengallis, George, Connell, Terry D.
Formato: Artigo
Idioma:Inglês
Publicado: 2010
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2862118/
https://ncbi.nlm.nih.gov/pubmed/20332049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2010.03.016
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