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Synthesis of Bi-substrate State Mimics of Dihydropteroate Synthase as Potential Inhibitors and Molecular Probes

The increasing emergence of resistant bacteria drives us to design and develop new antimicrobial agents. Pursuant to that goal, a new targeting approach of the dihydropteroate synthase enzyme, which serves as the site of action for the sulfonamide class of antimicrobial agents, is being explored. Us...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Qi, Jianjun, Virga, Kristopher G., Das, Sourav, Zhao, Ying, Yun, Mi-Kyung, White, Stephen W., Lee, Richard E.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2010
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3147184/
https://ncbi.nlm.nih.gov/pubmed/21216602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2010.12.003
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