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Multiplex Zymography Captures Stage-specific Activity Profiles of Cathepsins K, L, and S in Human Breast, Lung, and Cervical Cancer

BACKGROUND: Cathepsins K, L, and S are cysteine proteases upregulated in cancer and proteolyze extracellular matrix to facilitate metastasis, but difficulty distinguishing specific cathepsin activity in complex tissue extracts confounds scientific studies and employing them for use in clinical diagn...

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Autors principals: Chen, Binbin, Platt, Manu O
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3146840/
https://ncbi.nlm.nih.gov/pubmed/21756348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-9-109
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