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Systematic optimization of multiplex zymography protocol to detect active cathepsins K, L, S, and V in healthy and diseased tissue: compromise between limits of detection, reduced time, and resources

Cysteine cathepsins are a family of proteases identified in cancer, atherosclerosis, osteoporosis, arthritis and a number of other diseases. As this number continues to rise, so does the need for low cost, broad use quantitative assays to detect their activity and can be translated to the clinic in...

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Autors principals: Dumas, Jerald E., Platt, Manu O.
Format: Artigo
Idioma:Inglês
Publicat: 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3659237/
https://ncbi.nlm.nih.gov/pubmed/23532386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12033-013-9658-4
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