Calcineurin (CN) Activation Promotes Apoptosis of Glomerular Podocytes Both in Vitro and in Vivo

To determine the role of Gq signaling and calcineurin (CN) activation in promoting apoptosis of glomerular podocytes, constitutively active Gq [Gq(+)] or CN [CN(+)] proteins were introduced into cultured podocytes using protein transduction by tagging the proteins with the transactivator of transcri...

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Autori principali: Wang, Liming, Chang, Jae-Hyung, Paik, Seung-Yeol, Tang, Yuping, Eisner, William, Spurney, Robert F.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Endocrine Society 2011
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Original Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3146249/
https://ncbi.nlm.nih.gov/pubmed/21622531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2011-0029
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