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Regulation of cofilin phosphorylation in glomerular podocytes by testis specific kinase 1 (TESK1)

Expression of a constitutively active Rho A (V14Rho) in podocytes in vivo induces albuminuria and foot process (FP) effacement. These effects may be mediated by the Rho A effector Rho kinase (ROK); but inhibition of ROK with Y27632 failed to attenuate albuminuria or FP effacement in V14Rho mice. ROK...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Wang, Liming, Buckley, Anne F., Spurney, Robert F.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6095849/
https://ncbi.nlm.nih.gov/pubmed/30115939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-30115-3
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