Role of calcineurin (CN) in kidney glomerular podocyte: CN inhibitor ameliorated proteinuria by inhibiting the redistribution of CN at the slit diaphragm

Although calcineurin (CN) is distributed in many cell types and functions in regulating cell functions, the precise roles of CN remained in each type of the cells are not well understood yet. A CN inhibitor (CNI) has been used for steroid‐resistant nephrotic syndrome. A CNI is assumed to ameliorate...

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Udgivet i:Physiol Rep
Main Authors: Wakamatsu, Ayako, Fukusumi, Yoshiyasu, Hasegawa, Eriko, Tomita, Masayuki, Watanabe, Toru, Narita, Ichiei, Kawachi, Hiroshi
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2016
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4814882/
https://ncbi.nlm.nih.gov/pubmed/27009276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.12679
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