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Transcript assembly and abundance estimation from RNA-Seq reveals thousands of new transcripts and switching among isoforms
High-throughput mRNA sequencing (RNA-Seq) holds the promise of simultaneous transcript discovery and abundance estimation(1-3). We introduce an algorithm for transcript assembly coupled with a statistical model for RNA-Seq experiments that produces estimates of abundances. Our algorithms are impleme...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3146043/ https://ncbi.nlm.nih.gov/pubmed/20436464 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.1621 |
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